Helicobacter pylori infection is associated with worse severity of Parkinson's disease.
Identifieur interne : 000701 ( Main/Exploration ); précédent : 000700; suivant : 000702Helicobacter pylori infection is associated with worse severity of Parkinson's disease.
Auteurs : Ai Huey Tan [Malaisie] ; Sanjiv Mahadeva [Malaisie] ; Connie Marras [Canada] ; Abdul Malik Thalha [Malaisie] ; Chiun Khang Kiew [Malaisie] ; Chia Ming Yeat [Malaisie] ; Sheang Wen Ng [Malaisie] ; Sheau Phing Ang [Malaisie] ; Siew Kian Chow [Malaisie] ; Mun Fai Loke [Malaisie] ; Jamunarani S. Vadivelu [Malaisie] ; Norlinah Ibrahim [Malaisie] ; Hoi Sen Yong [Malaisie] ; Chong Tin Tan [Malaisie] ; Susan H. Fox [Canada] ; Anthony E. Lang [Canada] ; Shen-Yang Lim [Malaisie]Source :
- Parkinsonism & related disorders [ 1873-5126 ] ; 2015.
English descriptors
- KwdEn :
- Age Factors, Aged, Aged, 80 and over, Breath Tests, Female, Helicobacter Infections (physiopathology), Helicobacter pylori (pathogenicity), Humans, Male, Middle Aged, Parkinson Disease (microbiology), Parkinson Disease (physiopathology), Predictive Value of Tests, Quality of Life, Severity of Illness Index, Spectrophotometry, Infrared, Statistics, Nonparametric, Surveys and Questionnaires.
- MESH :
- microbiology : Parkinson Disease.
- pathogenicity : Helicobacter pylori.
- physiopathology : Helicobacter Infections, Parkinson Disease.
- Age Factors, Aged, Aged, 80 and over, Breath Tests, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Quality of Life, Severity of Illness Index, Spectrophotometry, Infrared, Statistics, Nonparametric, Surveys and Questionnaires.
Abstract
Some studies have suggested that chronic Helicobacter pylori (HP) infection can aggravate the neurodegenerative process in Parkinson's disease (PD), and targeted intervention could potentially modify the course of this disabling disease. We aimed to study the impact of HP infection on motor function, gastrointestinal symptoms, and quality of life in a large cohort of PD patients.
DOI: 10.1016/j.parkreldis.2014.12.009
PubMed: 25560322
Affiliations:
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Safra Program in Parkinson's Disease, Toronto Western Hospital, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital</wicri:regionArea><wicri:noRegion>Toronto Western Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Thalha, Abdul Malik" sort="Thalha, Abdul Malik" uniqKey="Thalha A" first="Abdul Malik" last="Thalha">Abdul Malik Thalha</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine (Division of Gastroenterology), University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Medicine (Division of Gastroenterology), University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Kiew, Chiun Khang" sort="Kiew, Chiun Khang" uniqKey="Kiew C" first="Chiun Khang" last="Kiew">Chiun Khang Kiew</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Yeat, Chia Ming" sort="Yeat, Chia Ming" uniqKey="Yeat C" first="Chia Ming" last="Yeat">Chia Ming Yeat</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Ng, Sheang Wen" sort="Ng, Sheang Wen" uniqKey="Ng S" first="Sheang Wen" last="Ng">Sheang Wen Ng</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Ang, Sheau Phing" sort="Ang, Sheau Phing" uniqKey="Ang S" first="Sheau Phing" last="Ang">Sheau Phing Ang</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Chow, Siew Kian" sort="Chow, Siew Kian" uniqKey="Chow S" first="Siew Kian" last="Chow">Siew Kian Chow</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Loke, Mun Fai" sort="Loke, Mun Fai" uniqKey="Loke M" first="Mun Fai" last="Loke">Mun Fai Loke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Microbiology, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Medical Microbiology, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Vadivelu, Jamunarani S" sort="Vadivelu, Jamunarani S" uniqKey="Vadivelu J" first="Jamunarani S" last="Vadivelu">Jamunarani S. Vadivelu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Microbiology, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Medical Microbiology, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Ibrahim, Norlinah" sort="Ibrahim, Norlinah" uniqKey="Ibrahim N" first="Norlinah" last="Ibrahim">Norlinah Ibrahim</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine (Division of Neurology), Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Medicine (Division of Neurology), Universiti Kebangsaan Malaysia, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Yong, Hoi Sen" sort="Yong, Hoi Sen" uniqKey="Yong H" first="Hoi Sen" last="Yong">Hoi Sen Yong</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Institute of Biological Sciences, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Tan, Chong Tin" sort="Tan, Chong Tin" uniqKey="Tan C" first="Chong Tin" last="Tan">Chong Tin Tan</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Fox, Susan H" sort="Fox, Susan H" uniqKey="Fox S" first="Susan H" last="Fox">Susan H. Fox</name><affiliation wicri:level="1"><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital</wicri:regionArea><wicri:noRegion>Toronto Western Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><affiliation wicri:level="1"><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital</wicri:regionArea><wicri:noRegion>Toronto Western Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Lim, Shen Yang" sort="Lim, Shen Yang" uniqKey="Lim S" first="Shen-Yang" last="Lim">Shen-Yang Lim</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia. Electronic address: limshenyang@ymail.com.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25560322</idno><idno type="pmid">25560322</idno><idno type="doi">10.1016/j.parkreldis.2014.12.009</idno><idno type="wicri:Area/PubMed/Corpus">000560</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000560</idno><idno type="wicri:Area/PubMed/Curation">000560</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000560</idno><idno type="wicri:Area/PubMed/Checkpoint">000560</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000560</idno><idno type="wicri:Area/Ncbi/Merge">001A20</idno><idno type="wicri:Area/Ncbi/Curation">001A20</idno><idno type="wicri:Area/Ncbi/Checkpoint">001A20</idno><idno type="wicri:Area/Main/Merge">000702</idno><idno type="wicri:Area/Main/Curation">000701</idno><idno type="wicri:Area/Main/Exploration">000701</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Helicobacter pylori infection is associated with worse severity of Parkinson's disease.</title><author><name sortKey="Tan, Ai Huey" sort="Tan, Ai Huey" uniqKey="Tan A" first="Ai Huey" last="Tan">Ai Huey Tan</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Mahadeva, Sanjiv" sort="Mahadeva, Sanjiv" uniqKey="Mahadeva S" first="Sanjiv" last="Mahadeva">Sanjiv Mahadeva</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine (Division of Gastroenterology), University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Medicine (Division of Gastroenterology), University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Marras, Connie" sort="Marras, Connie" uniqKey="Marras C" first="Connie" last="Marras">Connie Marras</name><affiliation wicri:level="1"><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital</wicri:regionArea><wicri:noRegion>Toronto Western Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Thalha, Abdul Malik" sort="Thalha, Abdul Malik" uniqKey="Thalha A" first="Abdul Malik" last="Thalha">Abdul Malik Thalha</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine (Division of Gastroenterology), University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Medicine (Division of Gastroenterology), University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Kiew, Chiun Khang" sort="Kiew, Chiun Khang" uniqKey="Kiew C" first="Chiun Khang" last="Kiew">Chiun Khang Kiew</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Yeat, Chia Ming" sort="Yeat, Chia Ming" uniqKey="Yeat C" first="Chia Ming" last="Yeat">Chia Ming Yeat</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Ng, Sheang Wen" sort="Ng, Sheang Wen" uniqKey="Ng S" first="Sheang Wen" last="Ng">Sheang Wen Ng</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Ang, Sheau Phing" sort="Ang, Sheau Phing" uniqKey="Ang S" first="Sheau Phing" last="Ang">Sheau Phing Ang</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Chow, Siew Kian" sort="Chow, Siew Kian" uniqKey="Chow S" first="Siew Kian" last="Chow">Siew Kian Chow</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Loke, Mun Fai" sort="Loke, Mun Fai" uniqKey="Loke M" first="Mun Fai" last="Loke">Mun Fai Loke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Microbiology, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Medical Microbiology, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Vadivelu, Jamunarani S" sort="Vadivelu, Jamunarani S" uniqKey="Vadivelu J" first="Jamunarani S" last="Vadivelu">Jamunarani S. Vadivelu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Microbiology, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Medical Microbiology, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Ibrahim, Norlinah" sort="Ibrahim, Norlinah" uniqKey="Ibrahim N" first="Norlinah" last="Ibrahim">Norlinah Ibrahim</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine (Division of Neurology), Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Department of Medicine (Division of Neurology), Universiti Kebangsaan Malaysia, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Yong, Hoi Sen" sort="Yong, Hoi Sen" uniqKey="Yong H" first="Hoi Sen" last="Yong">Hoi Sen Yong</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Institute of Biological Sciences, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Tan, Chong Tin" sort="Tan, Chong Tin" uniqKey="Tan C" first="Chong Tin" last="Tan">Chong Tin Tan</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author><author><name sortKey="Fox, Susan H" sort="Fox, Susan H" uniqKey="Fox S" first="Susan H" last="Fox">Susan H. Fox</name><affiliation wicri:level="1"><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital</wicri:regionArea><wicri:noRegion>Toronto Western Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name><affiliation wicri:level="1"><nlm:affiliation>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease, Toronto Western Hospital</wicri:regionArea><wicri:noRegion>Toronto Western Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Lim, Shen Yang" sort="Lim, Shen Yang" uniqKey="Lim S" first="Shen-Yang" last="Lim">Shen-Yang Lim</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur, Malaysia. Electronic address: limshenyang@ymail.com.</nlm:affiliation><country xml:lang="fr">Malaisie</country><wicri:regionArea>Division of Neurology and the Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, University of Malaya, Kuala Lumpur</wicri:regionArea><wicri:noRegion>Kuala Lumpur</wicri:noRegion></affiliation></author></analytic><series><title level="j">Parkinsonism & related disorders</title><idno type="eISSN">1873-5126</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age Factors</term><term>Aged</term><term>Aged, 80 and over</term><term>Breath Tests</term><term>Female</term><term>Helicobacter Infections (physiopathology)</term><term>Helicobacter pylori (pathogenicity)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (microbiology)</term><term>Parkinson Disease (physiopathology)</term><term>Predictive Value of Tests</term><term>Quality of Life</term><term>Severity of Illness Index</term><term>Spectrophotometry, Infrared</term><term>Statistics, Nonparametric</term><term>Surveys and Questionnaires</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Helicobacter pylori</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Helicobacter Infections</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Age Factors</term><term>Aged</term><term>Aged, 80 and over</term><term>Breath Tests</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Predictive Value of Tests</term><term>Quality of Life</term><term>Severity of Illness Index</term><term>Spectrophotometry, Infrared</term><term>Statistics, Nonparametric</term><term>Surveys and Questionnaires</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Some studies have suggested that chronic Helicobacter pylori (HP) infection can aggravate the neurodegenerative process in Parkinson's disease (PD), and targeted intervention could potentially modify the course of this disabling disease. We aimed to study the impact of HP infection on motor function, gastrointestinal symptoms, and quality of life in a large cohort of PD patients.</div></front></TEI><affiliations><list><country><li>Canada</li><li>Malaisie</li></country></list><tree><country name="Malaisie"><noRegion><name sortKey="Tan, Ai Huey" sort="Tan, Ai Huey" uniqKey="Tan A" first="Ai Huey" last="Tan">Ai Huey Tan</name></noRegion><name sortKey="Ang, Sheau Phing" sort="Ang, Sheau Phing" uniqKey="Ang S" first="Sheau Phing" last="Ang">Sheau Phing Ang</name><name sortKey="Chow, Siew Kian" sort="Chow, Siew Kian" uniqKey="Chow S" first="Siew Kian" last="Chow">Siew Kian Chow</name><name sortKey="Ibrahim, Norlinah" sort="Ibrahim, Norlinah" uniqKey="Ibrahim N" first="Norlinah" last="Ibrahim">Norlinah Ibrahim</name><name sortKey="Kiew, Chiun Khang" sort="Kiew, Chiun Khang" uniqKey="Kiew C" first="Chiun Khang" last="Kiew">Chiun Khang Kiew</name><name sortKey="Lim, Shen Yang" sort="Lim, Shen Yang" uniqKey="Lim S" first="Shen-Yang" last="Lim">Shen-Yang Lim</name><name sortKey="Loke, Mun Fai" sort="Loke, Mun Fai" uniqKey="Loke M" first="Mun Fai" last="Loke">Mun Fai Loke</name><name sortKey="Mahadeva, Sanjiv" sort="Mahadeva, Sanjiv" uniqKey="Mahadeva S" first="Sanjiv" last="Mahadeva">Sanjiv Mahadeva</name><name sortKey="Ng, Sheang Wen" sort="Ng, Sheang Wen" uniqKey="Ng S" first="Sheang Wen" last="Ng">Sheang Wen Ng</name><name sortKey="Tan, Chong Tin" sort="Tan, Chong Tin" uniqKey="Tan C" first="Chong Tin" last="Tan">Chong Tin Tan</name><name sortKey="Thalha, Abdul Malik" sort="Thalha, Abdul Malik" uniqKey="Thalha A" first="Abdul Malik" last="Thalha">Abdul Malik Thalha</name><name sortKey="Vadivelu, Jamunarani S" sort="Vadivelu, Jamunarani S" uniqKey="Vadivelu J" first="Jamunarani S" last="Vadivelu">Jamunarani S. Vadivelu</name><name sortKey="Yeat, Chia Ming" sort="Yeat, Chia Ming" uniqKey="Yeat C" first="Chia Ming" last="Yeat">Chia Ming Yeat</name><name sortKey="Yong, Hoi Sen" sort="Yong, Hoi Sen" uniqKey="Yong H" first="Hoi Sen" last="Yong">Hoi Sen Yong</name></country><country name="Canada"><noRegion><name sortKey="Marras, Connie" sort="Marras, Connie" uniqKey="Marras C" first="Connie" last="Marras">Connie Marras</name></noRegion><name sortKey="Fox, Susan H" sort="Fox, Susan H" uniqKey="Fox S" first="Susan H" last="Fox">Susan H. Fox</name><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E" last="Lang">Anthony E. Lang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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